49 studies found for:    "multiple system atrophy"
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Rank Status Study
21 Completed Motor Activation in Multiple System Atrophy and Parkinson Disease: a Positron Emission Tomography (PET) Study
Condition: Multisystemic Atrophy
Interventions: Radiation: H215O PET;   Drug: Levodopa
22 Recruiting Biomarkers in Parkinsonian Syndromes
Conditions: Parkinsonian Syndromes;   Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Interventions: Other: CSF, blood and urine sampling;   Other: clinical measures of disease severity and progression
23 Completed
Has Results
Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)
Conditions: Neurogenic Orthostatic Hypotension;   Non-Diabetic Autonomic Neuropathy;   Multiple System Atrophy;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Droxidopa;   Drug: Placebo
24 Active, not recruiting Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension
Conditions: Orthostatic Hypotension;   Pure Autonomic Failure;   Multiple System Atrophy;   Parkinson's Disease
Intervention:
25 Unknown  Diagnostic and Prognostic Biomarkers in Parkinson Disease
Conditions: Parkinson Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Intervention:
26 Completed Study About Efficacy and Safety to Treat Multi-System-Atrophy
Conditions: Multi-System-Atrophy;   Minocycline
Intervention: Drug: Minocyline
27 Terminated
Has Results
Augmenting Effects of L-DOPS With Carbidopa and Entacapone
Conditions: Parkinson Disease;   Multiple System Atrophy;   Autonomic Nervous System Diseases
Interventions: Drug: Droxidopa;   Drug: Carbidopa;   Drug: Entacapone
28 Enrolling by invitation Botulinum A Toxin in Patients With Parkinson's Disease
Conditions: Parkinson's Disease;   Multiple System Atrophy;   Detrusor Overactivity
Intervention: Drug: Intravesical injection of Botulinum A toxin
29 Recruiting The Role of Endothelin in the Supine Hypertension of Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: BQ123;   Drug: Bq123;   Drug: Saline
30 Completed Diagnosis and Natural History Study of Patients With Neurological Conditions
Conditions: Alzheimer's Disease;   Dementia;   Movement Disorder;   Multiple System Atrophy;   Parkinson's Disease
Intervention:
31 Recruiting Magnetic Resonance Spectroscopy in Autonomic Failure
Conditions: Pure Autonomic Failure;   Multiple System Atrophy
Intervention: Procedure: Magnetic Resonance Spectroscopy Imaging
32 Completed Analysis of the Enteric Nervous System Using Colonic Biopsies
Conditions: Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Intervention: Procedure: colonoscopy or rectosigmoidoscopy
33 Completed Autonomic Failure Patients for RNA Blood Sampling
Conditions: Pure Autonomic Failure;   Multiple System Atrophy;   Parkinson's Plus Syndromes
Intervention:
34 Completed Research of Biomarkers in Parkinson Disease
Conditions: Parkinson Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy;   Huntington Disease;   Dystonia;   Diffuse Lewy Body Disease
Intervention:
35 Completed Increased Gut Permeability to Lipopolysaccharides (LPS) in Parkinson's Disease
Conditions: Parkinson's Disease;   Multiple System Atrophy
Intervention:
36 Active, not recruiting Nebivolol in the Supine Hypertension of Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: Placebo;   Drug: Nebivolol 5 mg;   Drug: metoprolol tartrate 50 mg;   Drug: Sildenafil25 mg
37 Recruiting Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: Losartan;   Drug: Captopril;   Drug: Placebo
38 Unknown  Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes
Conditions: Parkinson's Disease;   Parkinsonian Syndrome;   Multiple System Atrophy;   Supranuclear Palsy, Progressive;   Essential Tremor;   Vascular Parkinsonism;   Drug Induced Parkinsonism
Intervention:
39 Recruiting Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI)
Conditions: Parkinson's Disease (PD);   Parkinsonism;   Progressive Supranuclear Palsy (PSP);   Multiple System Atrophy (MSA)
Intervention:
40 Recruiting A Clinical Study of Patients With Symptomatic NOH to Assess Sustained Effects of Droxidopa Therapy
Conditions: Symptomatic Neurogenic Orthostatic Hypotension;   Parkinson's Disease;   Multiple Systems Atrophy;   Pure Autonomic Failure;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Droxidopa;   Drug: Placebo

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Indicates status has not been verified in more than two years