9 studies found for:    "familial lipoprotein lipase deficiency"
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Rank Status Study
1 Recruiting Extension to a Randomized, Double-blind, Placebo Controlled Study of LCQ908 in Subjects With Familial Chylomicronemia Syndrome.
Condition: Familial Chylomicronemia Syndrome (FCS) (HLP Type I)
Intervention: Drug: LCQ908
2 Recruiting The APPROACH Study: A Study of ISIS-APOCIIIRx in Patients With Familial Chylomicronemia Syndrome
Condition: Familial Chylomicronemia Syndrome
Interventions: Drug: ISIS-APOCIIIRx;   Drug: Placebo
3 Recruiting Pilot Study To Assess CAT-2003 in Patients With Chylomicronemia
Conditions: Lipoprotein Lipase Deficiency, Familial;   Hyperlipoproteinemia Type I;   Chylomicronemia, Familial;   Hypertriglyceridemia
Interventions: Drug: CAT-2003;   Drug: Placebo
4 Completed A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome
Condition: Familial Chylomicronemia Syndrome (FCS)
Interventions: Drug: LCQ908;   Drug: Placebo
5 Unknown  Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X]
Condition: Familial Lipoprotein Lipase Deficiency
Interventions: Genetic: Alipogene Tiparvovec (AMT-011), Human LPL [S447X];   Drug: Mycophenolate mofetil;   Drug: cyclosporine
6 Completed Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects
Condition: Familial Lipoprotein Lipase Deficiency
Interventions: Genetic: Alipogene Tiparvovec (AMT-011), Human LPL [S447X];   Drug: mycophenolate mofetil;   Drug: cyclosporine;   Drug: methylprednisolone
7 Suspended Duration of Effect of Alipogene Tiparvovec Treatment, Which Was Administered in Other Studies
Condition: Hyperlipoproteinemia Type I
Intervention:
8 Enrolling by invitation Study to Re-assess and Re-confirm Data Previously Recorded About the Incidence and Severity of Acute Abdominal "Pancreatitis" Episodes in Lipoprotein Lipase Deficient (LPLD) Subjects Previously Enrolled on AMT Clinical Studies
Condition: Lipoprotein Lipase Deficiency
Intervention:
9 Completed Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia
Condition: Hyperlipoproteinemia
Interventions: Drug: LCQ908;   Drug: Placebo

Indicates status has not been verified in more than two years