83 studies found for:    "familial hypercholesterolemia"
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"familial hypercholesterolemia" (83 records)
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Rank Status Study
1 Recruiting Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada
Conditions: Familial Hypercholesterolemia;   Lipid Disorder
Intervention:
2 Active, not recruiting Long Term, Follow-on Study of Lomitapide in Patients With Homozygous Familial Hypercholesterolemia
Condition: Familial Hypercholesterolemia
Intervention: Drug: lomitapide
3 Withdrawn Effect of APL180 on Endothelial Function in Familial Hypercholesterolemia Patients
Condition: Familial Hypercholesterolemia
Interventions: Drug: APL180;   Drug: Placebo
4 Completed Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia
Conditions: Heterozygous Familial Hypercholesterolemia;   Mixed Dyslipidemia
Intervention: Drug: Fluvastatin
5 Active, not recruiting Effect of CER-001 on Plaque Volume in Homozygous Familial Hypercholesterolemia (HoFH) Subjects
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: CER-001
6 Terminated Implitapide in Patients With Homozygous Familial Hypercholesterolemia (HoFH) on Maximal Concurrent Lipid-Lowering Therapy
Condition: Familial Hypercholesterolemia
Intervention: Drug: Implitapide
7 Terminated Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy
Condition: Familial Hypercholesterolemia
Intervention: Drug: Implitapide
8 Recruiting The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository
Condition: Homozygous Familial Hypercholesterolemia
Intervention:
9 Recruiting A 52 Week Study To Assess The Use Of RN316 (PF-04950615) In Subjects With Heterozygous Familial Hypercholesterolemia
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: PF-04950615;   Other: Placebo
10 Unknown  Evaluation of Chylomicrons Metabolism in Sub-Clinical Atherosclerosis in Patients Whit Heterozigous Familial Hypercholesterolemia (FH) Treated With Statin Plus Ezetimibe
Condition: Heterozigous Familial Hypercholesterolemia
Intervention: Drug: Statins and Ezetimibe
11 Completed Efficacy of a New Symbiotic Formulation in Children With Familial Hypercholesterolemia
Conditions: Dyslipidemia;   Familial Hypercholesterolemia
Interventions: Dietary Supplement: Lactobacillus paracasei B21060;   Other: low satured diet
12 Not yet recruiting French Observatory of Familial Hypercholesterolemia in Cardiology
Condition: Familial Hypercholesterolemia
Intervention:
13 Not yet recruiting Gene Analysis and Treatment Optimization in Chinese Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Other: Gene analysis
14 Completed Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities
Condition: Homozygous Familial Hypercholesterolemia
Interventions: Biological: Evolocumab (AMG145);   Other: Placebo
15 Terminated
Has Results
A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158)
Conditions: Hypercholesterolemia, Familial;   Heterozygous Familial Hypercholesterolemia
Intervention: Drug: MK-0524A
16 Completed
Has Results
A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: AEGR-733
17 Completed Study to Assess the Tolerability and Efficacy of Anacetrapib Co-administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)
Conditions: Hyperlipoproteinemia Type II;   Heterozygous Familial Hypercholesterolemia
Interventions: Drug: Anacetrapib;   Drug: Placebo for Anacetrapib
18 Active, not recruiting Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042)
Conditions: Hyperlipoproteinemia Type II;   Homozygous Familial Hypercholesterolemia
Interventions: Drug: Anacetrapib;   Drug: Placebo
19 Active, not recruiting Study of Alirocumab (REGN727/ SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: LMT (atorvastatin, simvastatin, or rosuvastatin);   Drug: alirocumab (REGN727/ SAR236553);   Drug: placebo
20 Completed An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia
Condition: Familial Hypercholesterolaemia
Intervention: Drug: rosuvastatin calcium

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Indicates status has not been verified in more than two years