88 studies found for:    "familial hypercholesterolemia"
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Rank Status Study
21 Active, not recruiting Study of Alirocumab (REGN727/ SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: LMT (atorvastatin, simvastatin, or rosuvastatin);   Drug: alirocumab (REGN727/ SAR236553);   Drug: placebo
22 Completed An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia
Condition: Familial Hypercholesterolaemia
Intervention: Drug: rosuvastatin calcium
23 Unknown  Postprandial Lipid Metabolism in Familial Hypercholesterolaemia:Effects of Fish Oils
Conditions: Hypertriglyceridaemia;   Familial Hypercholesterolaemia
Interventions: Dietary Supplement: Fish oil capsule;   Drug: HMG Coenzyme reductase
24 Completed A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-on Therapy to Their Existing Medication
Condition: Familial Hypercholesterolemia
Interventions: Drug: Colesevelam hydrochloride film-coated tablets;   Drug: Placebo
25 Not yet recruiting A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia (HoFH)
Interventions: Drug: Rouvastatin 20mg;   Drug: Placebo
26 Completed A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050)
Condition: Heterozygous Familial Hypercholesterolemia (HeFH)
Interventions: Drug: Anacetrapib;   Drug: Placebo for anacetrapib
27 Completed Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial Hypercholesterolemia
Condition: Familial Hypercholesterolemia
Intervention: Procedure: gene therapy
28 Completed Exploratory Study of Plaque Regression
Condition: Heterozygous Familial Hypercholesterolemia
Intervention: Drug: CER-001
29 Completed Atorvastatin Three Year Pediatric Study
Condition: Familial Hypercholesterolemia
Intervention: Drug: atorvastatin
30 Recruiting Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders
Condition: Severe Familial Hypercholesterolemia
Intervention: Biological: Evolocumab (AMG145)
31 Completed
Has Results
PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatin
Condition: Familial Hypercholesterolemia
Interventions: Drug: Rosuvastatin;   Drug: Placebo
32 Completed
Has Results
Efficacy and Safety Study of ISIS 301012 (Mipomersen) as Add-on in Familial Hypercholesterolemic Patients With Coronary Artery Disease
Conditions: Heterozygous Familial Hypercholesterolemia;   Coronary Artery Disease
Interventions: Drug: mipomersen sodium;   Drug: placebo
33 Unknown  Soy Food Intervention Trial
Condition: Familial Hypercholesterolemia
Interventions: Dietary Supplement: soy protein diet;   Dietary Supplement: rapeseed oil
34 Unknown  Effect of Rapeseed Oil and Sunflower Oil
Condition: Familial Hypercholesterolemia
Interventions: Dietary Supplement: rapeseed oil;   Dietary Supplement: sunflower oil
35 Not yet recruiting Effect of Omega-3 Fatty Acid on Endothelial Function
Condition: Familial Hypercholesterolemia
Interventions: Drug: Omega-3;   Drug: placebo
36 Terminated Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease. This Study is Also Known as CAPTIVATE.
Conditions: Atherosclerosis;   Heterozygous Familial Hypercholesterolemia
Intervention: Drug: Pactimibe sulfate
37 Recruiting Efficacy and Safety of Lomitapide in Japanese Patients With HoFH on Concurrent Lipid-Lowering Therapy
Condition: Familial Hypercholesterolemia - Homozygous
Intervention: Drug: lomitapide
38 Terminated Efficacy and Safety Study of Eprotirome in HeFH Patients Who Are on Optimal Standard of Care
Condition: Heterozygous Familial Hypercholesterolaemia
Interventions: Drug: Placebo;   Drug: Eprotirome
39 Completed Efficacy and Safety of JTT-705 300, 600 And 900mg in Comparison With Placebo in Patients With Type II Hyperlipidaemia
Condition: Type II Hyperlipidaemia
Interventions: Drug: Placebo;   Drug: JTT-705 300mg;   Drug: JTT-705 600mg;   Drug: JTT-705 900mg
40 Completed Efficacy and Safety Study of JTT-705 in Combination With Pravastatin 40 mg in Patients With Type II Hyperlipidemia
Condition: Type II Hyperlipidemia
Interventions: Drug: JTT-705 600 mg and pravastatin 40 mg;   Drug: JTT-705 300 mg and pravastatin 40 mg;   Drug: Placebo and pravastatin 40 mg

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Indicates status has not been verified in more than two years