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7 studies found for:    "dopamine beta-hydroxylase deficiency"

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Rank Status Study
1 Completed A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH);   Non-diabetic Neuropathy;   Primary Autonomic Failure;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Placebo;   Drug: Droxidopa
2 Completed Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH);   Non-diabetic Neuropathy;   Primary Autonomic Failure;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Placebo;   Drug: Droxidopa
3 Completed Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)
Conditions: Neurogenic Orthostatic Hypotension;   Non-Diabetic Autonomic Neuropathy;   Multiple System Atrophy;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Droxidopa;   Drug: Placebo
4 Completed Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) (Droxi-304)
Conditions: Primary Autonomic Failure;   Dopamine Beta Hydroxylase Deficiency;   Non-Diabetic Neuropathy;   Neurogenic Orthostatic Hypotension
Intervention: Drug: Droxidopa
5 Active, not recruiting The Pathophysiology of Orthostatic Hypotension
Conditions: Autonomic Nervous System Diseases;   Orthostatic Hypotension;   Dopamine Beta-Hydroxylase Deficiency;   Orthostatic Intolerance
Interventions: Procedure: Standing or upright tilt;   Procedure: Microneurography;   Procedure: QSweat;   Device: neck cuff stimulation;   Drug: phenylephrine,isoproterenol,nitroprusside,propranolol,edrophonium,atropine,tyramine;   Drug: clonidine,yohimbine,metoclopramide,alpha-methyldopa;   Procedure: BodPod;   Procedure: Eye exam;   Procedure: Sleep study;   Procedure: Pain response testing;   Procedure: Metabolic chamber;   Procedure: Brain function studies;   Procedure: Bicycle Exercise Test
6 Recruiting Treatment of Orthostatic Hypotension
Conditions: Autonomic Nervous System Diseases;   Orthostatic Hypotension;   Dopamine Beta-Hydroxylase Deficiency;   Orthostatic Intolerance
Interventions: Drug: droxidopa;   Drug: placebo;   Drug: alpha-methyldopa;   Drug: carbidopa;   Drug: metyrosine;   Drug: levodopa;   Drug: atomoxetine;   Drug: metoclopramide
7 Terminated Augmenting Effects of L-DOPS With Carbidopa and Entacapone
Conditions: Parkinson Disease;   Multiple System Atrophy;   Autonomic Nervous System Diseases
Intervention: Drug: L-DOPS
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† Indicates status has not been verified in more than two years