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37 studies found for:    "chronic granulomatous disease"

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Rank Status Study
1 Recruiting Gene Therapy for Chronic Granulomatous Disease
Condition: Chronic Granulomatous Disease
Intervention: Drug: Phagocyte Oxidase Subunit Transduced CD34 Hematopoietic Stem Cells
2 Recruiting Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease
Condition: Chronic Granulomatous Disease
Interventions: Drug: Busulfan;   Biological: alemtuzumab;   Drug: Cyclophosphamide;   Drug: Fludarabine;   Drug: cyclosporine;   Procedure: stem cell infusion
3 Completed Stem Cell Transplant Following Low-Intensity Chemotherapy to Treat Chronic Granulomatous Disease
Condition: Chronic Granulomatous Disease
Interventions: Device: Nexell Isolex with T-cell Depletion;   Device: Baxter isolex 300i
4 Recruiting Radiofrequency Ablation for Liver Abscesses From Chronic Granulomatous Disease
Conditions: Radiofrequency Ablation;   Liver Abscesses -Staphylococcus Infection;   CGD;   Chronic Granulomatous Disease;   RFA
Interventions: Procedure: RFA - Radiofrequency Ablation;   Procedure: Scans - Liver;   Procedure: Liver;   Procedure: Drawn
5 Recruiting Assessment of the Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease
Conditions: IFN-Gamma Therapy;   CGD Gene Mutation;   CGD Response to IFNg;   Chronic Granulomatous Disease;   Immunodeficiency Disease
Intervention: Drug: IFN-gamma
6 Completed Treatment of Chronic Granulomatous Disease With Allogeneic Stem Cell Transplantation Versus Standard of Care
Condition: Chronic Granulomatous Disease
Intervention: Drug: T-Cell Depleted & CD34+Select/w/StemCell Enriched Product
7 Active, not recruiting Gene Therapy for Chronic Granulomatous Disease in Korea
Condition: Chronic Granulomatous Disease
Intervention: Drug: Autologous hematopoietic stem cells transduced with MT-gp91 retroviral vector
8 Completed Gene Therapy for X-linked Chronic Granulomatous Disease (CGD) in Children
Condition: Chronic Granulomatous Disease
Intervention: Genetic: retroviral SF71-gp91phox transduced CD34+ cells
9 Completed Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up
Conditions: Chronic Granulomatous Disease;   Communicable Disease
Interventions: Drug: Gene Therapy Method for CGD;   Device: Isolex 300i Magnetic Cell Selector
10 Completed A Phase IV Study of Recombinant Human Gamma Interferon in Patients With Chronic Granulomatous Diseases of Childhood
Condition: Chronic Granulomatous Disease
Intervention: Drug: interferon-gamma
11 Completed Modified Stem Cell Transplantation Procedure for Treating Chronic Granulomatous Disease
Condition: Chronic Granulomatous Disease
Intervention: Procedure: Stem cell transplantation
12 Completed Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous Disease
Conditions: Chronic Granulomatous Disease;   Crohn'S-like IBD;   Inflammatory Bowel Disease (IBD)
Intervention: Drug: Infliximab
13 Completed Pharmacokinetics of Posaconazole in Children With Chronic Granulomatous Disease (CGD)
Condition: Chronic Granulomatous Disease
Intervention: Drug: posaconazole (PSZ)
14 Active, not recruiting Gene Therapy for X-linked Chronic Granulomatous Disease (X-CGD)
Condition: X-Linked Chronic Granulomatous Disease
Intervention: Genetic: X vivo gene therapy
15 Recruiting Targeted Busulfan, Fludarabine Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Chronic Granulomatous Disease(CGD)
Condition: Chronic Granulomatous Disease
Intervention: Drug: Busulfan
16 Withdrawn Lentiviral Gene Therapy for X-Linked Chronic Granulomatous Disease (X-CGD)
Condition: Granulomatous Disease, Chronic, X-linked, Variant
Intervention: Genetic: pCCLchimGp91s lentiviral vector transduced CD34+ cells infusion
17 Unknown † Gene Therapy for Chronic Granulomatous Disease
Condition: Granulomatous Disease, Chronic
Intervention: Drug: retroviral SF71-gp91phox transduced CD34+ cells
18 Completed Learning and Behavior Problems in Children With Chronic Granulomatous Disease and Related Disorders
Conditions: Chediak Higashi Syndrome;   Chronic Granulomatous Disease;   Job's Syndrome;   Leukocyte Disorder
Intervention:
19 Recruiting Use of G-CSF to Obtain Blood Cell Precursors
Conditions: Chronic Granulomatous Disease;   Healthy;   Immunologic Disease;   Leukocyte Adhesion Deficiency Syndrome;   Severe Combined Immunodeficiency
Intervention:
20 Terminated Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
Conditions: Immunologic Deficiency Syndromes;   Chediak-Higashi Syndrome;   Common Variable Immunodeficiency;   Graft Versus Host Disease;   X-Linked Lymphoproliferative Syndrome;   Familial Erythrophagocytic Lymphohistiocytosis;   Hemophagocytic Lymphohistiocytosis;   X-linked Agammaglobulinemia;   Wiskott-Aldrich Syndrome;   Chronic Granulomatous Disease;   X-linked Hyper IgM Syndrome;   Severe Combined Immunodeficiency;   Leukocyte Adhesion Deficiency Syndrome;   Virus-Associated Hemophagocytic Syndrome
Interventions: Drug: anti-thymocyte globulin;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: etoposide;   Drug: methotrexate;   Drug: methylprednisolone;   Drug: prednisone;   Procedure: Allogeneic Bone Marrow Transplantation
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† Indicates status has not been verified in more than two years