193 studies found for:    "Thalassemia"
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Rank Status Study
1 Completed Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN)
Conditions: Anemia, Cooley's;   Beta-Thalassemia;   Hematologic Diseases;   Thalassemia;   Osteoporosis;   Iron Overload;   Hypertension, Pulmonary
Interventions: Drug: Deferoxamine;   Drug: Deferiprone;   Drug: Arginine;   Drug: Sildenafil;   Drug: Decitabine
2 Active, not recruiting Prevalence of Pulmonary Hypertension (PAH) in Patients With Thalassemia
Conditions: Thalassemia Major;   Thalassemia Intermedia;   Pulmonary Arterial Hypertension
Intervention: Other: Physician standard-of-care according to ESC/ERS Guidelines
3 Recruiting Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.
Conditions: Beta Thalassemia Major;   Beta Thalassemia Intermedia
Interventions: Drug: Dose level 1a;   Drug: Dose level 1b;   Drug: Dose level 2;   Drug: dose level 3;   Drug: dose level 4;   Drug: dose level 5
4 Unknown  Beta-thalassemia and Microparticles
Conditions: Thalassemia Major (TM);   Thalassemia Intermedia (TI);   Microparticles (MP)Originating From Platelets, Endothelial Cells and Monocytes
Intervention: Other: Physiopathology
5 Completed Efficacy and Safety of Neridronate (Nerixia®)to Treat Osteoporosis in Patients With TM and TI
Conditions: Osteoporosis;   Thalassemia Major;   Thalassemia Intermedia
Intervention: Drug: Neridronate
6 Recruiting Allogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemia, THALLO
Condition: Thalassemia
Interventions: Drug: Busulfan;   Drug: Fludarabine;   Drug: Campath 1H;   Drug: Cyclophosphamide;   Drug: MESNA
7 Completed Efficacy Study of the Use of Sequential DFP-DFO Versus DFP
Conditions: Beta-Thalassemia;   Thalassemia Major
Interventions: Drug: Deferiprone (DFP) and Deferoxamine (DFO);   Drug: Deferiprone (DFP)
8 Terminated Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia
Conditions: Hemoglobinopathies;   Anemia, Sickle Cell;   Hemoglobin SC Disease;   Thalassemia;   Thalassemia Major
Interventions: Drug: Busulfan;   Drug: Fludarabine;   Drug: FK506;   Drug: Prednisone
9 Completed 5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia
Condition: Beta Thalassemia
Intervention: Drug: 5-Azacytidine
10 Completed Evaluating People With Thalassemia: The Thalassemia Longitudinal Cohort (TLC) Study
Condition: Thalassemia
Intervention:
11 Recruiting Endocrine and Nutritional Assessment in B Thalassemia Major
Condition: Thalassemia
Intervention: Other: Nutritional recommendations
12 Completed Effect of Antioxidant Cocktail in Beta-thalassemia/Hb E Patients
Condition: Thalassemia
Interventions: Drug: curcuminoids, N-acetylcysteine, deferiprone and vitamin E;   Drug: Curcuminoids and alpha-tocopherol
13 Unknown  Amlodipine in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major
Conditions: Thalassemia;   Iron Overload
Intervention: Drug: Amlodipine
14 Completed
Has Results
Evaluating the Safety and Effectiveness of Decitabine in People With Thalassemia Intermedia
Condition: Thalassemia
Intervention: Drug: Decitabine (USAN, INN)
15 Unknown  Stem Cell Transplant in Sickle Cell Disease and Thalassemia
Conditions: Sickle Cell Disease;   Beta Thalassemia
Interventions: Drug: Busulfan;   Drug: Fludarabine;   Drug: Alemtuzumab;   Procedure: Allogeneic stem cell transplant
16 Completed A Study of Long-term Treatment With Deferasirox in Patients With Beta-thalassemia and Transfusional Hemosiderosis
Conditions: Beta-Thalassemia;   Hemosiderosis
Intervention: Drug: deferasirox
17 Recruiting Iron Overload and Growth Velocity in Thalassemia and Sickle Cell Anemia
Conditions: Thalassemia;   Sickle Cell Disease
Intervention: Other: Medical Chart Summary
18 Completed Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-Thalassemia
Condition: Beta-Thalassemia
Interventions: Drug: Deferitrin (GT56-252);   Drug: desferoxamine (DFO)
19 Completed Effect of Metoprolol on Thalassemia Cardiomyopathy
Condition: B Thalassemia
Interventions: Drug: metoprolol;   Drug: placebo
20 Unknown  Zoledronic Acid for the Prevention of Bone Loss Post-bone Marrow Transplantation for Thalassemia Major Patients
Conditions: Beta-Thalassemia;   Bone Marrow Transplantation
Interventions: Drug: Zoledronic acid;   Drug: Placebo

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