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388 studies found for:    "Lupus"

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1 Recruiting Safety Study of AMG 811 in Subjects With Discoid Lupus Erythematosus
Conditions: Cutaneous Lupus;   Discoid Lupus;   Lupus;   Systemic Lupus Erythematosus
Interventions: Drug: AMG811;   Drug: AMG811 Placebo
2 Recruiting Safety and Efficacy of Topical R333 in Patients With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE) Lesions
Conditions: Lupus Erythematosus, Discoid;   Lupus Erythematosus, Systemic
Interventions: Drug: R932333;   Drug: Placebo
3 Completed Safety and Efficacy Study of LJP 394 (Abetimus Sodium) to Treat Lupus Kidney Disease
Conditions: Immunologic Diseases;   Autoimmune Diseases;   Systemic Lupus Erythematosus;   Lupus Nephritis;   Lupus Glomerulonephritis
Intervention: Drug: Abetimus sodium (LJP 394)
4 Completed A Study of the Safety and Pharmacokinetics of CNTO 136 in Patients With Cutaneous Lupus Erythematosus and Systemic Lupus Erythematosus
Conditions: Lupus Erythematosus, Cutaneous;   Lupus Erythematosus, Systemic
Interventions: Drug: 1 mg/kg CNTO 136;   Drug: 4 mg/kg CNTO 136;   Drug: 10 mg/kg CNTO 136;   Drug: Placebo
5 Unknown † Cutaneous Lupus Erythematosus and Elidel
Conditions: Lupus Erythematosus, Cutaneous;   Lupus Erythematosus, Discoid
Intervention: Drug: Elidel (pimecrolimus)
6 Not yet recruiting Phase Ib Study of SC Milatuzumab in SLE
Conditions: Lupus Erythematosus, Cutaneous;   Lupus Erythematosus, Discoid;   Lupus Erythematosus, Systemic;   Lupus Vasculitis, Central Nervous System;   Lupus Nephritis
Intervention: Drug: milatuzumab
7 Recruiting Multicenter Study Assessing the Efficacy & Safety of Hydroxychloroquine Sulfate in Patients With Systemic Lupus Erythematosus or Cutaneous Lupus Erythematosus With Active Lupus Erythematosus Specific Skin Lesion
Condition: Cutaneous Lupus Erythematosus-Systemic Lupus Erythematosus
Interventions: Drug: hydroxychloroquine (Z0188);   Drug: Placebo
8 Recruiting Safety Study of AMG 557 in Subjects With Subacute Cutaneous Lupus Erythematosus
Conditions: Cutaneous Lupus;   Lupus
Interventions: Drug: AMG 557;   Drug: AMG 557 Placebo
9 Active, not recruiting Abatacept and Cyclophosphamide Combination Therapy for Lupus Nephritis
Conditions: Lupus Nephritis;   Lupus Erythematosus, Systemic
Interventions: Drug: Abatacept;   Drug: cyclophosphamide;   Drug: azathioprine;   Drug: prednisone;   Drug: abatacept placebo;   Drug: azathioprine placebo
10 Recruiting Study of Systemic Lupus Erythematosus
Conditions: Lupus Nephritis;   Systemic Lupus Erythematosus
Intervention:
11 Completed Treating Systemic Lupus Erythematosus (SLE) Patients With CTLA4-IgG4m (RG2077)
Conditions: Lupus Erythematosus, Systemic;   Lupus Nephritis
Interventions: Drug: CTLA4-IgG4m (RG2077);   Drug: Cyclophosphamide
12 Terminated Study of LJP 394 in Lupus Patients With History of Renal Disease
Conditions: Lupus Erythematosus, Systemic;   Lupus Nephritis
Interventions: Drug: abetimus sodium (LJP 394) and/or placebo solution;   Drug: abetimus sodium (LJP 394);   Drug: Phosphate-buffered saline
13 Recruiting Safety Study of AMG 557 in Subjects With Lupus Arthritis
Condition: Lupus Arthritis, Systemic Lupus Erythematosus
Interventions: Drug: AMG 557 210 mg;   Drug: 210 mg Matching Placebo;   Drug: AMG 557 140 mg;   Drug: 140 mg Matching Placebo
14 Completed Cyclophosphamide and Fludarabine to Treat Lupus Nephritis
Conditions: Glomerulonephritis;   Lupus Nephritis;   Systemic Lupus Erythematosus
Intervention: Drug: SQ Fludarabine
15 Completed Cyclosporine A or Intravenous Cyclophosphamide for Lupus Nephritis: The Cyclofa-Lune Study
Conditions: Systemic Lupus Erythematosus;   Lupus Nephritis
Interventions: Drug: Cyclosporine A;   Drug: Cyclophosphamide
16 Recruiting Efficacy and Safety of Belimumab in Patients With Active Lupus Nephritis
Conditions: Lupus Nephritis;   Systemic Lupus Erythematosus;   SLE
Interventions: Biological: Placebo plus standard therapy;   Biological: Belimumab 10 mg/kg plus standard therapy;   Drug: Standard therapy
17 Completed Tacrolimus for the Treatment of Systemic Lupus Erythematosus With Membranous Nephritis
Conditions: Lupus Nephritis;   Lupus Erythematosus, Systemic
Intervention: Drug: tacrolimus
18 Terminated TNF Blockade With Remicade in Active Lupus Nephritis WHO Class V (TRIAL )
Conditions: Lupus Erythematosus, Systemic;   Lupus Nephritis
Interventions: Drug: infliximab;   Drug: placebo
19 Not yet recruiting Trial of Rituximab and Mycophenolate Mofetil Without Oral Steroids for Lupus Nephritis
Condition: Systemic Lupus Erythematosus, Lupus Nephritis
Interventions: Drug: Oral prednisolone;   Drug: Rituximab;   Drug: Mycophenolate mofetil;   Drug: Methyl prednisolone
20 Unknown † Duke Lupus Registry
Conditions: Systemic Lupus Erythematosus;   Cutaneous Lupus
Intervention:
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† Indicates status has not been verified in more than two years