312 studies found for:    "Hemophilia A"
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Rank Status Study
1 Not yet recruiting An Open-label Safety and Efficacy Study of Recombinant FVIII in Patients With Severe Hemophilia A
Conditions: Hemophilia A;   Severe Hemophilia A
Intervention: Biological: rVIII‑SingleChain
2 Completed
Has Results
Efficacy and Safety Study of Prophylactic Versus On-Demand Treatment With Feiba NF in Subjects With Hemophilia A or B and a High Titer Inhibitor
Conditions: Hemophilia A;   Hemophilia B;   (High-titer) Factor VIII Inhibitor;   (High-titer) Factor IX Inhibitor
Intervention: Biological: Factor VIII Inhibitor Bypassing Activity (nanofiltered, vapor heat-treated)
3 Terminated Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Congenital Hemophilia A
Condition: Hemophilia A
Intervention: Biological: OBI-1
4 Completed Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Acquired Hemophilia A
Condition: Hemophilia A
Intervention: Biological: OBI-1
5 Terminated Trial of Rituximab Versus Oral Cyclophosphamide to Eradicate or Suppress Autoimmune Anti-Factor VIII Antibodies in Acquired Hemophilia A
Condition: Hemophilia A
Interventions: Drug: Rituxan;   Drug: prednisone
6 Completed Efficacy and Safety of Recombinant Factor VIII (GreenGene) in Patients With Hemophilia A
Condition: Hemophilia A
Intervention: Drug: GreenGene
7 No longer available Expanded Access to B-Domain Deleted Recombinant Porcine Factor VIII (OBI-1) in the Treatment of Acquired Hemophilia A Due to Factor VIII Inhibitory Auto-antibodies
Condition: Acquired Hemophilia A
Intervention: Biological: OBI-1
8 Active, not recruiting Study of Recombinant Coagulation Factor VIII Fc Fusion Protein, BIIB 031, in Pediatric PTP Subjects With Hemophilia A
Condition: Hemophilia A
Intervention: Drug: rFVIIIFc
9 Completed
Has Results
Study Evaluating B-Domain Deleted Recombinant Factor VIII (BDDrFVIII, ReFacto AF) in Patients With Hemophilia A Undergoing Elective Major Surgery
Condition: Hemophilia A
Intervention: Biological: ReFacto AF
10 Recruiting Phase 3/4 Study of a Recombinant Protein-Free Factor VIII (rAHF-PFM): Comparison of Continuous Infusion Versus Intermittent Bolus Infusion in Hemophilia A Subjects Undergoing Major Orthopedic Surgery
Condition: Hemophilia A
Intervention: Drug: Recombinant Protein-Free Factor VIII (rAHF-PFM)
11 Completed Study of Pharmacokinetics, Efficacy, and Safety of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Pediatric Patients With Hemophilia A
Condition: Hemophilia A
Intervention: Drug: Antihemophilic factor, recombinant, manufactured protein-free
12 Completed
Has Results
Efficacy and Safety Study of a Recombinant Protein-Free Manufactured Factor VIII (rAHF-PFM) in Previously Untreated Hemophilia A Patients
Condition: Hemophilia A
Intervention: Biological: Recombinant Antihemophilic Factor Manufactured and Formulated without Added Human or Animal Proteins (rAHF-PFM)
13 Completed Study Comparing Blood Levels of ReFacto and Advante in Hemophilia A
Condition: Hemophilia A
Interventions: Drug: ReFacto;   Drug: Advante
14 Completed Efficacy and Safety Study of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Pediatric Patients in Canada With Hemophilia A - A Continuation of Baxter Study 060101
Condition: Hemophilia A
Intervention: Drug: Antihemophilic Factor Manufactured and Formulated without Added Human or Animal Proteins (rAHF-PFM)
15 Completed Study to Establish Bioequivalence of ReFacto AF (BDDrFVIII) With Advate (FLrFVIII) in Hemophilia A
Condition: Hemophilia A
Interventions: Genetic: ReFacto AF;   Genetic: B-Domain deleted Recombinant Factor VIII;   Genetic: BDDrFVIII
16 Completed Health Related Quality of Life of Youth and Young Adults With Hemophilia A
Condition: Hemophilia A
Intervention:
17 Completed A Trial Investigating the Pharmacokinetics and Pharmacodynamics of rFVIIa in Patients With Haemophilia A or B With or Without Inhibitors
Conditions: Congenital Bleeding Disorder;   Haemophilia A;   Haemophilia A With Inhibitors;   Haemophilia B;   Haemophilia B With Inhibitors
Intervention: Drug: eptacog alfa (activated)
18 Completed Study Evaluating ReFacto® in Hemophilia A Undergoing Major Surgery
Condition: Hemophilia A
Intervention: Drug: ReFacto
19 Completed Pharmacokinetics, Efficacy and Safety Study of IMMUNATE SD (Human Plasma-Derived Coagulation Factor VIII Concentrate) in Hemophilia A Patients
Condition: Hemophilia A
Intervention: Drug: Human Plasma-Derived Coagulation Factor VIII Concentrate (Virus Inactivated by Polysorbate 80 Treatment and Vapor Heat Treatment)
20 Completed Clot Formation and Clot Stability in Patients With Severe Haemophilia A
Condition: Hemophilia A
Intervention: Drug: ReFacto (Recombinant factor VIII) and Tranexamic acid

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Indicates status has not been verified in more than two years