62 studies found for:    "Fanconi anemia"
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Rank Status Study
21 Terminated Safety and Efficacy Trial of Danazol in Patients With Fanconi Anemia or Dyskeratosis Congenita
Conditions: Fanconi Anemia;   Dyskeratosis Congenita
Intervention: Drug: danazol
22 Recruiting HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy
Conditions: Fanconi Anemia;   Severe Marrow Failure;   Myelodysplastic Syndrome (MDS);   Acute Myelogenous Leukemia (AML)
Interventions: Drug: Busulfan;   Drug: Cyclophosphamide;   Drug: Fludarabine;   Drug: rabbit ATG;   Drug: G-CSF;   Biological: Peripheral blood stem cell
23 Completed Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100
Condition: Fanconi Anemia
Interventions: Drug: AMD3100;   Device: AmCell CliniMACs
24 Terminated Use of Rft5-Dga to Deplete Alloreactive Cells for Pts With Fanconi Anemia After Haploidentical SCT
Condition: FANCONI ANEMIA
Interventions: Procedure: CD34 selected haploidentical PBSCT;   Drug: Fludarabine;   Biological: T cell infusion;   Biological: Campath 1h;   Biological: anti-CD45
25 Active, not recruiting Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed by Unrelated Donor Stem Cell Transplant in Treating Patients With Fanconi Anemia
Conditions: Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Childhood Acute Myeloid Leukemia in Remission;   Childhood Myelodysplastic Syndromes;   Fanconi Anemia;   Previously Treated Myelodysplastic Syndromes
Interventions: Drug: fludarabine phosphate;   Drug: cyclosporine;   Radiation: total-body irradiation;   Procedure: allogeneic bone marrow transplantation;   Procedure: allogeneic hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Drug: mycophenolate mofetil
26 Active, not recruiting Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant, Mycophenolate Mofetil, and Cyclosporine in Treating Patients With Fanconi Anemia
Conditions: Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Childhood Acute Myeloid Leukemia in Remission;   Childhood Myelodysplastic Syndromes;   de Novo Myelodysplastic Syndromes;   Fanconi Anemia;   Previously Treated Myelodysplastic Syndromes
Interventions: Drug: fludarabine phosphate;   Drug: cyclophosphamide;   Radiation: total-body irradiation;   Procedure: allogeneic bone marrow transplantation;   Drug: mycophenolate mofetil;   Drug: cyclosporine;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation;   Other: laboratory biomarker analysis
27 Completed Hematopoietic Stem Cell Transplantation for Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using Total Body Irradiation, Cyclophosphamide and Fludarabine
Condition: Fanconi Anemia
Intervention: Drug: Cyclophosphamide and Fludarabine
28 Unknown  Fanconi Anemia Transplant Lacking Genotypically Identical Donor
Condition: Fanconi Anemia
Intervention: Device: Miltenyi CliniMACs device
29 Recruiting Multicenter Transplant Study for Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Drug: Chemotherapy Preparative Regimen;   Biological: Miltenyi CliniMACS
30 Unknown  Phase I Study of Amifostine in Patients With Bone Marrow Failure Related to Fanconi's Anemia
Condition: Fanconi's Anemia
Intervention: Drug: amifostine
31 Completed Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Fanconi's Anemia
Condition: Fanconi's Anemia
Interventions: Drug: cyclophosphamide;   Procedure: Allogeneic Bone Marrow Transplantation
32 Completed Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia
Conditions: Fanconi's Anemia;   Myelodysplastic Syndromes;   Leukemia, Nonlymphocytic, Acute;   Leukemia, Lymphocytic, Acute
Interventions: Drug: cyclophosphamide;   Procedure: Allogeneic Bone Marrow Transplantation
33 Unknown  Phase I Pilot Study of CD34 Enriched, Fanconi's Anemia Complementation Group C Gene Transduced Autologous Peripheral Blood Stem Cell Transplantation in Patients With Fanconi's Anemia
Condition: Fanconi's Anemia
Interventions: Drug: filgrastim;   Genetic: Autologous stem cells transduced with FACC retroviral vector;   Procedure: Autologous Stem Cell Transplantation
34 Completed Fanconi Syndrome Due to ARVs in HIV-Infected Persons
Conditions: HIV Infections;   Fanconi Syndrome;   Kidney Disease;   Renal Impairment
Intervention: Procedure: Blood Draws
35 Completed Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia
Condition: Fanconi's Anemia
Interventions: Drug: anti-thymocyte globulin;   Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: filgrastim;   Drug: fludarabine;   Drug: methylprednisolone
36 Completed Evaluation of Fanconi Syndrome and Cystinosis
Conditions: Cystinosis;   Fanconi Syndrome
Intervention:
37 Terminated Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer
Conditions: Chronic Myeloproliferative Disorders;   Diamond-blackfan Anemia;   Fanconi Anemia;   Graft Versus Host Disease;   Leukemia;   Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
Interventions: Drug: anti-thymocyte globulin;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: filgrastim;   Drug: melphalan;   Drug: methylprednisolone;   Drug: mycophenolate mofetil;   Procedure: radiation therapy;   Procedure: umbilical cord blood transplantation
38 Completed Busulfan, Antithymocyte Globulin, and Fludarabine Followed By a Donor Stem Cell Transplant in Treating Young Patients With Blood Disorders, Bone Marrow Disorders, Chronic Myelogenous Leukemia in First Chronic Phase, or Acute Myeloid Leukemia in First Remission
Conditions: Congenital Amegakaryocytic Thrombocytopenia;   Diamond-blackfan Anemia;   Fanconi Anemia;   Leukemia;   Severe Congenital Neutropenia;   Thrombocytopenia
Interventions: Biological: anti-thymocyte globulin;   Drug: busulfan;   Drug: fludarabine phosphate;   Procedure: allogeneic bone marrow transplantation;   Procedure: peripheral blood stem cell transplantation;   Procedure: umbilical cord blood transplantation;   Radiation: radiation therapy
39 Unknown  Assessing Immune Function in Young Patients With Cytopenia That Did Not Respond to Treatment
Conditions: Dyskeratosis Congenita;   Fanconi Anemia;   Myelodysplastic Syndromes;   Nonmalignant Neoplasm;   Pearson Marrow-pancreas Syndrome;   Shwachman-diamond Syndrome
Interventions: Genetic: polymerase chain reaction;   Other: flow cytometry;   Other: immunologic technique;   Procedure: biopsy
40 Suspended Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation
Conditions: Thalassemia;   Sickle Cell Disease;   Glanzmann Thrombasthenia;   Wiskott-Aldrich Syndrome;   Chronic-granulomatous Disease;   Severe Congenital Neutropenia;   Leukocyte Adhesion Deficiency;   Schwachman-Diamond Syndrome;   Diamond-Blackfan Anemia;   Fanconi Anemia;   Dyskeratosis-congenita;   Chediak-Higashi Syndrome;   Severe Aplastic Anemia
Intervention: Drug: Alefacept

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