22 studies found for:    "Dysgammaglobulinemia" OR "X-linked hyper IgM syndrome"
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Rank Status Study
1 Unknown  Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders
Conditions: X-Linked Agammaglobulinemia;   X-Linked Hyper IgM Syndrome;   Wiskott-Aldrich Syndrome;   Leukocyte Adhesion Deficiency Syndrome
Intervention:
2 Terminated Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
Conditions: Immunologic Deficiency Syndromes;   Chediak-Higashi Syndrome;   Common Variable Immunodeficiency;   Graft Versus Host Disease;   X-Linked Lymphoproliferative Syndrome;   Familial Erythrophagocytic Lymphohistiocytosis;   Hemophagocytic Lymphohistiocytosis;   X-linked Agammaglobulinemia;   Wiskott-Aldrich Syndrome;   Chronic Granulomatous Disease;   X-linked Hyper IgM Syndrome;   Severe Combined Immunodeficiency;   Leukocyte Adhesion Deficiency Syndrome;   Virus-Associated Hemophagocytic Syndrome
Interventions: Drug: anti-thymocyte globulin;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: etoposide;   Drug: methotrexate;   Drug: methylprednisolone;   Drug: prednisone;   Procedure: Allogeneic Bone Marrow Transplantation
3 Terminated Studies of Disorders in Antibody Production and Related Primary Immunodeficiency States
Conditions: Hyper-IgM Syndrome;   Ectodermal Dysplasia
Intervention:
4 Active, not recruiting A Study to Find Out How Safe and Effective Gammaplex® is in Young People With Primary Immunodeficiency
Conditions: Primary Immune Deficiency Disorders;   Common Variable Immunodeficiency;   X-linked Agammaglobulinemia;   Hyper-IgM Syndrome;   Wiskott-Aldrich Syndrome
Intervention: Biological: Gammaplex
5 Completed Study of Immune Responses and Safety of Recombinant Human CD40 Ligand in Patients With X-Linked Hyper-IgM Syndrome
Condition: Immunoproliferative Disorder
Interventions: Drug: Bacteriophage;   Drug: rhuCD40L;   Drug: KLH
6 Not yet recruiting Reduced Intensity Conditioning for Children and Adults With Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (PIDs) (BMT Clinical Trials Network 1204)
Conditions: Hemophagocytic Lymphohistiocytosis;   CAEBV;   Chronic Granulomatous Disease;   HIGM-1;   Leukocyte Adhesion Deficiency;   IPEX
Intervention: Biological: Hematopoietic Stem Cell Transplant
7 Recruiting Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
Conditions: Severe Combined Immunodeficiency;   Omenn's Syndrome;   Reticular Dysgenesis;   Wiskott-Aldrich Syndrome;   Bare Lymphocyte Syndrome;   MHC Class II Deficiency;   Common Variable Immunodeficiency;   Chronic Granulomatous Disease;   CD40 Ligand Deficiency;   Hyper IgM Syndrome;   X-linked Lymphoproliferative Disease;   Hemophagocytic Lymphohistiocytosis;   Combined Immune Deficiencies;   Griscelli Syndrome;   Chediak-Higashi Syndrome;   Langerhan's Cell Histiocytosis
Interventions: Drug: Alemtuzumab 0.3 mg;   Drug: Cyclophosphamide;   Drug: Busulfan;   Biological: Stem Cell Transplantation;   Drug: Fludarabine phosphate 40 mg;   Drug: Melphalan;   Drug: Alemtuzumab 0.2 mg;   Drug: Fludarabine phosphate 30 mg;   Drug: MESNA
8 Recruiting Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary Immunodeficiency Diseases
Conditions: Primary Immune Deficiency Disorders;   Common Variable Immunodeficiency;   X-linked Agammaglobulinaemia;   Hyper-IgM Syndrome
Interventions: Biological: Gammaplex (5%);   Biological: Gammaplex 10
9 Completed Efficacy and Safety of Intravenous Immunoglobulin IVIG-F10 in Patients With Primary Immunodeficiencies (PID)
Conditions: Agammaglobulinemia;   IgG Deficiency;   Common Variable Immunodeficiency
Intervention: Drug: Immunoglobulins Intravenous (Human)
10 Active, not recruiting Treatment of Deficient Subclass or Anti-polysaccharide Antibody Response
Conditions: IgG Deficiency;   Infections
Interventions: Drug: intravenous immunoglobulins;   Drug: antibiotics
11 Completed Efficacy and Safety of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)
Conditions: Agammaglobulinemia;   IgG Deficiency;   Common Variable Immunodeficiency
Intervention: Drug: Immunoglobulins Intravenous (Human)
12 Not yet recruiting IVIG Treatment for Asthmatic Patients With IgG Subclass Deficiency
Condition: Asthma
Intervention: Drug: Immune Globulin
13 Completed B-Lymphocyte Stimulator (BLyS) To Treat Selective IgA Deficiency
Condition: IgA Deficiency
Intervention: Drug: B-Lymphocyte Stimulator (BLyS)
14 Completed
Has Results
Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases.
Conditions: Primary Immunodeficiency;   Common Variable Hypogammaglobulinemia;   X-linked Hypogammaglobulinemia;   Hypogammaglobulinemia;   Immunodeficiency With Hyper-IgM;   Wiskott-Aldrich Syndrome
Intervention: Biological: Gammaplex (Intravenous immunoglobulin)
15 Completed
Has Results
Safety and Efficacy of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)
Conditions: Agammaglobulinemia;   IgG Deficiency;   Common Variable Immunodeficiency
Intervention: Drug: Immunoglobulins Intravenous (Human)
16 Completed Efficacy of IgIv in Patients With IgG Subclass Deficiency and Recurrent Infections
Conditions: IgG Deficiency;   Infections
Intervention: Drug: IV Gamunex 10%
17 Recruiting PNEUMOCELL - Conjugated Pneumococcal Vaccination in Patients With Immunoglobulin G-deficiency
Condition: IgG Deficiency
Intervention: Biological: Prevenar13
18 Recruiting Molecular and Clinical Studies of Primary Immunodeficiency Diseases
Condition: Immunologic Deficiency Syndrome
Intervention:
19 Unknown  Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells
Conditions: Sickle Cell Disease;   Thalassemia;   Anemia;   Granuloma;   Wiskott-Aldrich Syndrome;   Chediak Higashi Syndrome;   Osteopetrosis;   Neutropenia;   Thrombocytopenia;   Hurler Disease;   Niemann-Pick Disease;   Fucosidosis
Intervention: Procedure: Hematopoietic stem cell transplantation
20 Completed A Clinical Study of the PK, Efficacy and Safety of Omr-IgG-am IGIV in Subjects With Primary Immune Deficiency Diseases
Condition: Immunologic Deficiency Syndromes
Intervention: Drug: Intravenous Immune Globulin

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Indicates status has not been verified in more than two years