Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
11 studies found for:    "Bannayan-Riley-Ruvalcaba syndrome" OR "Hamartoma Syndrome, Multiple"
Show Display Options
Rank Status Study
1 Completed
Has Results
Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes
Conditions: Cowden's Disease;   Hamartoma Syndrome, Multiple
Interventions: Radiation: fludeoxyglucose F 18;   Drug: sirolimus;   Other: Clinical Videography
2 Completed A Phase I/II Study of BGT226 in Adult Patients With Advanced Solid Malignancies Including Patients With Advanced Breast Cancer
Conditions: Solid Tumors;   Breast Cancer;   Cowden Syndrome
Intervention: Drug: BGT226
3 Completed A Phase I/II Study of BEZ235 in Patients With Advanced Solid Malignancies Enriched by Patients With Advanced Breast Cancer
Conditions: Breast Cancer,;   Advanced Solid Tumors,;   Cowden Syndrome
Intervention: Drug: BEZ235
4 Completed The Evaluation of Oral Acitretin in the Treatment of Psoriasis, Cutaneous Disorders of Keratinization, Multiple Basal Cell Carcinomas and Other Retinoid Responsive Diseases
Conditions: Basal Cell Carcinoma;   Keratosis Palmaris et Plantaris;   Psoriasis
Intervention:
5 Active, not recruiting A Study of Two Vismodegib Regimens in Patients With Multiple Basal Cell Carcinomas
Condition: Basal Cell Carcinoma
Interventions: Drug: placebo;   Drug: vismodegib
6 Active, not recruiting Trial Comparing the Effects of Intermittent Vismodegib Versus Photodynamic Therapy in Patients With Multiple Basal Cell Carcinomas
Conditions: Basal Cell Nevus Syndrome;   Gorlin's Syndrome
Interventions: Drug: GDC-0449;   Procedure: Aminolevulinic acid %20 topical solution + blue light
7 Terminated Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.
Conditions: Basal Cell Carcinoma;   Nevoid Basal Cell Carcinoma Syndrome;   Gorlin Syndrome
Intervention: Drug: verteporfin PDT
8 Unknown  French Digestive Polyposis Cohorte Family Adenomatous Polyposis With APC and MYH Gene Mutations , Cowden's Disease With PTEN Gene Mutation, Peutz Jeghers Disease With STK 11 Gene Mutation ,juvénil Polyposis With SMAD 4 Gene Mutation , Serrated and Hyperplastic Polyposis
Condition: Quality of Life
Interventions: Other: Procedure surgery behavioral and genetic diagnosis;   Procedure: quality of life after different type of surgery
9 Completed Informed Consent for Whole Genome Sequencing: Ideals and Norms Referenced by Early Participants
Conditions: Coronary Artery Disease;   Proteus Syndrome;   Coffin - Sins Syndrome;   Familial Isolated Hyperparathyroidism;   Dubouitz Syndrome
Intervention:
10 Recruiting Study of Proteus Syndrome and Related Congenital Disorders
Conditions: Growth Disorder;   Mental Retardation;   Multiple Abnormalies
Intervention:
11 Recruiting Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer
Conditions: Familial Ovarian Cancer;   Familial Breast Cancer;   BRCA1-associate Malignancies;   BRCA2-associated Malignancies
Intervention:

Indicates status has not been verified in more than two years